Sativex is an oromucosal
spray with flexible dosing1

Patients can tailor
their dose to give them
the right balance
of symptom relief
and mobility1

Flexible dosing
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Titration

Patients should increase the dose by
1 spray per day, up to a maximum of
12 sprays per day, until they achieve the right balance of symptom relief and mobility1

 

There should be at least a 15-minute gap between sprays1

Day

 

Sprays in the morning
(waking to 12:00)
Sprays in the evening
(16:00 to bedtime)
Total sprays per day

 

1 0 1 1
2 0 1 1
3 0 2 2
4 0 2 2
5 1 2 3
6 1 3 4
7 1 4 5
8 2 4 6
9 2 5 7
10 3 5 8
11 3 6 9
12 4 6 10
13 4 7 11
14 5 7 12

Maintenance

Patients should continue with their optimum dose1

 

Sprays can be spread throughout the day depending on patients’ response and tolerability1

 

If patients’ symptoms or concomitant medications change, they can adjust their dose of Sativex1