Sativex is an oromucosal spray
with flexible dosing1

Administration
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There are just
3 steps for patients
to follow1

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1. Gently shake the bottle1

 


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2. Point the blue marker on the nozzle under the tongue or towards the inside of the cheek1
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3. Press the nozzle to
spray Sativex once1

 

 

 

Patients can tailor
their dose to give them
the right balance
of symptom relief
and mobility1

Flexible dosing
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Titration

Patients should increase the dose by
1 spray per day, up to a maximum of
12 sprays per day, until they achieve the right balance of symptom relief and mobility1

 

There should be at least a 15-minute gap between sprays1

Day

 

Sprays in the morning
(waking to 12:00)
Sprays in the evening
(16:00 to bedtime)
Total sprays per day

 

1 0 1 1
2 0 1 1
3 0 2 2
4 0 2 2
5 1 2 3
6 1 3 4
7 1 4 5
8 2 4 6
9 2 5 7
10 3 5 8
11 3 6 9
12 4 6 10
13 4 7 11
14 5 7 12
 

Maintenance

Patients should continue with their optimum dose1

 

Sprays can be spread throughout the day depending on patients’ response and tolerability1

 

If patients’ symptoms or concomitant medications change, they can adjust their dose of Sativex1

 

 

Storage
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Sativex is easy to carry
and doesn’t need to be
kept in the fridge once
it is opened1

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Sativex comes in small, discreet bottles1

 

The bottles should be kept in the fridge before they are opened1

 

Once they are opened patients can carry the bottle with them as they do not need to be kept in the fridge anymore1

 

Each bottle should be used within 42 days of opening it1